Dysbiosis, through the lack of appropriate immunoregulatory and barrier factors, such as, e.g., short-chain fatty acids, causes inappropriate activation of the immune system, resulting in epithelial inflammation, epithelial barrier damage and disease development [55, 57,58,59,60,61]
They are also at higher risk of developing pernicious anaemia, a condition where antibodies are produces against the carrier of vitamin B12 in the gut, intrinsic factor
multiple injections require additional units
Exclude oxygen by overlaying with nitrogen or argon if available, and minimize headspace in storage vials
Hence, there remains an urgent need for bigger multi-centric RCTs evaluating the durability of weight loss with cagrisema and cagrilintide over many years of clinical use
minimize exposure