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A more is better approach driven by patients or confusion resulting in overdosing has been documented in studies of other diseases and may, in the case of oral cancer therapies, lead to substantially increased toxicity

The association between papillary thyroid carcinoma and histologically proven Hashimoto's thyroiditis: a meta-analysis

Journal of Environmental Science and Health

& Wietzerbin, J

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Additionally, heterogeneous astrocytes distributed throughout the brain exacerbate disease progression and compromise the BBB by releasing inflammatory factors and chemokines [55, 56]