orlistat glp 1 Obesity pharmacotherapy from the @TheAACE diabetes algorithm: GLP‑1/GIP and GLP‑1 RAs produce ~10–20% weight loss with A1c reduction, while older agents like phentermine, orlistat, and naltrexone/bupropion have less efficacy and safety trade‑offs Orlistat vs. Ozempic®: Differences and
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)













