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The duration of cycles and breaks depends on the specific study design

And this often is a form factor as you outlined or it could be dosing dynamics of a patient is not getting the outcome that theyre hoping for, are they experiencing side effects that are intolerable

IGF-1 also helps guard against giving too high a dose

GOT1 knockout combined with cysteine depletion by erastin or IKE showed potent antitumor effects against these cells by reducing GSH and increasing ferroptosis 66

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