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Monitor fasting glucose and HbA1c, as GH pathway stimulation can impact insulin sensitivity

A: With DAC: Longer half-life (~710 days), fewer injections needed Without DAC: Shorter action, may require more frequent dosing Both forms promote GH release but differ in dosing schedules and duration

Prolonged stimulation of GH and IGF-1 by CJC-1295 in healthy adults J Clin Endocrinol Metab (2006) Ionescu M et al

This mechanism not only lowers blood sugar but does so in a way that is independent of insulin, offering a significant advantage for people whose body's ability to use insulin is impaired