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If tau protein is pathologically reduced, it would cause iron ion transport disorder, thereby leading to ferroptosis in cells
That structure makes tirzepatide a therapeutic peptide or peptide-based biologic rather than a small molecule drug
Treatment of mice with DS-induced colitis (resembling human ulcerative colitis) with the human GLP-2 analog h(Gly 2 )GLP, twice daily for 10 days, reverses weight loss independent on food intake, decreases interleukin-1 expression and increased colon length, crypt depth, and mucosal area compared to treatment with saline (Drucker et al., 1999)
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