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The lactate shuttle hypothesis further revealed its pivotal roles in oxidative substrate transport and cellular signaling via monocarboxylate transporters (MCTs), leading to its recognition as a potent signaling metabolite, particularly through its receptor GPR81 (6-8)

Lindahl, P., Johansson, B

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Sublingual semaglutide may be beneficial for those looking to manage their weight loss when used alongside diet and exercise

These improvements occurred even though there was no significant difference in body mass index (BMI) between the GLP-1 RA group and the conventional treatment group at follow-up