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While these mechanisms can be helpful for diabetes control and weight loss, they can also cause side effects

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The STEP trial program examining higher-dose semaglutide (2.4 mg weekly) for weight management demonstrated mean weight loss of 12% to 15% over 68 weeks in adults with obesity, significantly exceeding placebo

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The researchers found a possible explanation: these drugs may increase activity in the brains serotonin system, particularly at a receptor called 5-HT2C, which can dampen sexual desire

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