GWAS, Genome-wide association studies
Hou GJ, Li CN, Liu SN, Huan Y, Liu Q, Sun SJ, Li LY, Hou SC, Shen ZF (2013) Long-term treatment with EXf, a peptide analog of Exendin-4, improves beta-cell function and survival in diabetic KKAy mice
It is given once weekly via a subcutaneous injection and works by activating both GLP-1 and GIP receptors a dual-action approach that produced among the most significant weight loss results seen in any modern clinical trial
Signs include itching or hives beyond the immediate injection area, difficulty breathing, or facial swelling
Contains no added sugar, starch, wheat, yeast, preservatives, artificial flavor
These SCFAs bind to specific receptors on L-cells, notably the free fatty acid receptors FFAR2 and FFAR3, which directly stimulate GLP-1 secretion