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The tb500 bpc 157 blend is used in non-clinical laboratory studies involving cytoskeletal signaling, peptide-mediated cellular interaction modeling, and angiogenesis-related pathway research

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In contrast, mechanisms supported by weak or preliminary evidence [e.g., the vitamin C/gut microbiota/depression axis (152, 153), and the calcium/gut microbiota/depression axis (218220)] require further validation

DS: Investigation, Writing original draft, Writing review and editing

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