Ideal candidates might include those who: Have documented binge eating episodes causing significant distress Meet BMI criteria for weight management medications Have not responded adequately to psychological interventions (such as cognitive behavioural therapy) Do not have contraindications to GLP-1 therapy Understand the off-label nature of this indication UK SmPCs for GLP-1 medications note findings of thyroid C-cell tumours in rodent studies, though the relevance to humans remains uncertain
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However, people may notice minor side effects like bloating and cramping
Its action is mediated by a specific GLP-1 receptor
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Semaglutide 2.4 mg weekly demonstrated significant weight loss in adolescents with obesity in the STEP TEENS trial