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a , Relative metabolite abundance of indicated whole cell or ER metabolites from ER-tag or control-tag HEK293T

394,395,396 In a phase Ib clinical study, the objective response rate (ORR) for pembrolizumab in patients was 18%, the median PFS was 2 months, and the median OS was 13 months

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The interactions between drugs and disease targets were visualized using Venny 2.1 to generate a Venn diagram, revealing 17 drug-disease targets (Figure 5C)

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