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Rats were randomized and divided into four groups that were subjected to sham surgery (control), OVX, or assigned randomly to receive HPL ethanol extract therapy (HPL-H: OVX + HPL extract 300 mg/kg/d, HPL-L: OVX + HPL extract 80 mg/kg/d)

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Treatment-related adverse events predict improved clinical outcome in NSCLC patients on KEYNOTE-001 at a single center

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Exley R and Cragg SJ

Studies have shown that NOS knockout aggravates bleomycin (BLM)-induced fibrosis, whereas NO supplementation mitigates tissue damage [82]