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Figure 1 2.1 Genetic factors and ethnic variations Genetic predisposition is a major contributor to UC

Drugs are identified and reported using a unique, three-segment number called the National Drug Code (NDC) which serves as the FDAs identifier for drugs

Cystine appeared to be the main regulator of GSH homeostasis (among other amino acids), since cystine deprivation alone reduced intracellular GSH and it was not further aggravated by depletion of other amino acids

ACKNOWLEGEMENTS This work was supported in part by National Institutes of Health grants HL116263 and HL127173