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Cardiovascular efficacy of sitagliptin in patients with diabetes at high risk of cardiovascular disease: a 12-month follow-up

This study showed that GLP-1 receptor agonist use was associated with markedly diminished risks of cirrhosis (aHR: 0.72, 95%CI: 0.66-0.79) and HCC (aHR: 0.65, 95%CI: 0.56-0.76) compared to non-use throughout a mean observation period of 4.8 years, with benefits observed across different baseline liver disease stages [57]

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Shaking denatures the peptide and destroys its effectiveness