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Long-term Safety: The long-term effects of triple receptor activation are still under investigation

Upregulation of cystathionine-beta-synthase in colonic epithelia reprograms metabolism and promotes carcinogenesis

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Identification of the metabolic differences between microbial pathogens and their hosts, as well as the design of species-specific antimicrobial agents targeting the differential metabolic pathways, therefore represent the most promising fields of research and are strongly supported by recent developments in biological methodology and system biology that allow a better understanding of pathogenic mechanisms at various levels [8, 22, 59]

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