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Targeting the Trem2-APOE pathway can restore the homeostatic signature of microglia in ALS and AD mouse models, potentially preventing neuronal loss and promote tolerogenic T-cell response (Krasemann et al., 2017)

Signed written informed consent was obtained from each volunteer before screening processes for this study

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Front Cell Infect Microbiol 11:755925 Asher S (2022) Periodontal health, cognitive decline, and dementia: a systematic review and meta-analysis of longitudinal studies

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