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J Neurosci 31(17):65876594 Hansen HH, Barkholt P, Fabricius K, Jelsing J, Terwel D, Pyke C, Knudsen LB, Vrang N (2016) The GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy

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doi: 10.1016/j.ebiom.2023.104642, 3 AronneL

This pattern mirrors findings with Semaglutide and Tirzepatide, where discontinuation leads to weight regain in the majority of cases

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Risks One of the risks that has been discovered with GLP-1 agonists is an increased risk of thyroid cancer, specifically medullary thyroid carcinoma