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337 The accumulation of inflammation and bone destruction affect the ability of cartilage endplates to provide nutrients to IVD, exacerbating IDD

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Focused experiments conducted in rat striatum synaptosome preparations have reported that melatonin inhibits the excitatory response in a partially Ca 2+ -dependent manner in which the direct effect on membrane hyperpolarization promoted intracellular Ca 2+ influx reduction 94

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[DOI] [PubMed] [Google Scholar] 77.Kakei M, Yada T, Nakagawa A, Nakabayashi H