Their most common side-effects include vomiting, diarrhea, and other gastrointestinal symptoms
Clinical studies suggest tirzepatide, sold as Zepbound, may lead to greater average weight loss than semaglutide, sold as Wegovy, for some patients
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Unregulated or poorly compounded injections carry higher risks
The efficacy analysis set included data from the mITT population excluding patients who discontinued the study drug because of inadvertent enrolment and data after initiating rescue medication (for severe persistent hyperglycaemia) or early discontinuation of study drug
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