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Interestingly, a recent study showed that CDK4/6 inhibitors blocked SLC7A11 expression by inhibiting SP1 binding to the SLC7A11 promoter and induced ferroptosis in luminal A breast cancer cells [31]

The population pharmacokinetic parameters are expressed as mean (coefficient of variation)

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Fibroblasts are responsible for extracellular matrix production, including collagen and elastin