Allosteric glutaminase inhibitors based on a 1,4-di(5-amino-1,3,4-thiadiazol-2-yl)butane scaffold
Diabetes 60 , 15611565 (2011)
Numerous studies demonstrated that this small molecule is crucial in many different human diseases such as aging, diabetes, acquired immune deficiency syndrome (AIDS), as well as neurodegenerative and liver diseases (30)
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In fact, GLP-1 receptors are present in the brain, including regions involved in learning, memory, and motor control
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