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Inhibition of poly-(ADP-ribose) polymerase protects the kidney in a canine model of endotoxic shock

Molecular mediators governing iron-copper interactions

# Source: supplementary webappendix to Gadde KM, Allison DB, Ryan DH, et al

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In response to such stress, Nuclear factor erythroid 2-related factor 2 (NRF2) acts as a key transcription factor, coordinating multiple intracellular antioxidant defense systems by directly or indirectly regulating the expression of downstream target genes such as GPX4, thereby safeguarding cells from ferroptosis

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