In controlled laboratory settings, it is utilized to study the relationship between NNMT inhibition, NAD+ biosynthesis, and cellular energy metabolism
As a result, eating a restrictive diet, such as a strict vegetarian or vegan diet, can lead to B12 deficiency
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Baseline B12 and folate assessment may help provide context for why some patients experience suboptimal outcomes with GLP-1 therapy, even when medications are dosed correctly
The resulting anemia is known as megaloblastic anemia and is the symptom for which the disease, pernicious anemia, was named (3)
Its role in promoting tissue regeneration and enhancing nerve function can be beneficial for some individuals