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These medications are also linked to changes in insulin response and blocking glucagon secretion, which plays a role in how the body manages blood sugar

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Other associated effects of GLP-1 include the inhibition of glucagon secretion by pancreatic cells, reduced gastric emptying and intestinal transit, the suppression of appetite, enhanced satiety and further functions in other tissues (see Drucker, 2018

Phentermine is a classic weight loss medication that was widely used before the rise of GLP-1 receptor agonists

In a clinical trial called SURMOUNT-5, people who used Zepbound over 72 weeks lost 20.2% of their body weight, compared to 13.7% in people who used Wegovy