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14 Agency Focus The reorganization of the FDAs Office of Regulatory Affairs (ORA) into the Office of Inspections and Investigations (OII) was implemented on October 1, 2024

Thyroid Tumors GLP-1 receptor agonists, including those used in Wegovy and Mounjaro, carry a potential risk of thyroid C-cell tumours

Like the STEP 1 to STEP 4 studies, STEP 5 was a DB placebo-controlled trial, although it was not pivotal and, thus, did not meet the inclusion criteria for the systematic review

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Increased water intake and dietary fibre are recommended

Fine white/off-white powder with a mild sulfurous note