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A small number (less than 5%) have respiratory-onset ALS, where breathing muscles weaken early, and these cases tend to be more severe
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This effect may involve several mechanisms, including repairing the intestinal barrier, regulating intestinal hormones, and providing anti-inflammation and antioxidation
Most community sources reporting visible physique changes describe multiple cycles spaced by the standard 4-week washout typically 3-4 cycles over 4-6 months