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R Phase I creates reactive intermediates through oxidation, reduction, and hydrolysis (mostly via cytochrome P450 enzymes)

This stress damages essential cellular components, including lipids, proteins, and DNA, potentially culminating in oxidative cell death

The high percentage of BrdU-incorporated -cells in exendin-4-treated mice suggests that the increased -cell mass mainly results from augmentation of -cell proliferation

Deboever N, McGrail DJ, Lee Y, Tran HT, Mitchell KG, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Swisher SG , Vaporciyan AA, Walsh GL, Bernatchez C, Vailati Negrao M, Zhang J, Wistuba II, Heymach JV, Cascone T, Gibbons DL, Haymaker CL, Sepesi B

Leiomyoma simultaneously impair endometrial BMP-2-mediated decidualization and anticoagulant expression through secretion of TGF-3

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