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For instance, as red blood cell production accelerates (typically beginning 3-5 days after treatment starts), iron stores may be utilised more rapidly

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Parenteral vitamin B12 is the recommended treatment and will be required for the remainder of the patient's life

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A 2025 pilot study published in PubMed confirmed short-term tolerance in 2 participants at 20mg intravenously, though the sample size remains too limited for definitive safety conclusions

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