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History of pancreatitis: Doctors most often avoid GLP-1 agonists in people with a history of pancreatitis since GLP-1 agonists may increase the risk of fatal hemorrhagic and necrotizing pancreatitis

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Lopez G, Torres K, Liu J, Hernandez B, Young E, Belousov R, et al

Common options include topical brightening agents, chemical peels, laser treatments, and oral supplements