The amylin signaling pathway is distinct from and complementary to GLP-1 receptor signaling, as amylin primarily influences hedonic appetite pathways (reward-driven eating) while GLP-1 primarily affects homeostatic appetite regulation
Because weight loss in general involves some reduction in muscle mass, an overly aggressive push to lose weight may make a person who is already at risk of sarcopenia more likely to develop it
The piperacillin component of piperacillin plus tazobactam interacts with methotrexate and can result in increased methotrexate serum levels due to the competition of penicillin with methotrexate for excretion sites in renal tubules
Livera G, Rouiller-Fabre V, Pairault C, Levacher C, Habert R
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doi:10.3945/ajcn.117.157107 41