But what we wanted to understand is what theyre doing in the brain. Key findings GLP-1 drugs act not only on metabolic pathways but also on brain circuits linked to reward Researchers identified a pathway connecting the hindbrain, central amygdala and dopamine-producing neurons The drugs reduce not just hunger, but the desire for high-calorie, rewarding foods Findings may help explain both therapeutic benefits and side effects such as nausea or reduced pleasure Beyond appetite suppression GLP-1 receptor agonists were originally developed to treat Type 2 diabetes by improving insulin response, with weight loss emerging as a secondary benefit
Anti-Aging Benefits CJC 1295 Ipamorelin can help slow down the aging process by promoting the production of collagen, which is essential for healthy skin, hair, and nails
Personalized medicine approaches can target supplementation based on individual genetics or skin type
These are active areas of investigation
Annu Rev Med , 2004, 55: 395-417
The first draft of the manuscript was written by Razia Sardar and Fatima Sardar, and it was reviewed by all other authors (Nor-Ashikin Mohamed Noor Khan, Fathiah Abdullah, and Yuhaniza Shafinie Kamsani)
