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Aged mice were intraperitoneally injected with 5 mg/kg FOXO4-DRI or PBS as a control every other day for three administrations, and effects were assessed 30 days post-treatment

Some people notice the morning mirror looks different inside the first week

Limited clinical validation: Despite decades of research interest, DSIP has not progressed into wide-scale clinical adoption, which raises questions about consistency and reproducibility of effects

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Circadian Rhythm Influence: DSIP positively influences circadian clock genes and proteins, suggesting it may help regulate biological rhythms in ways that extend beyond immediate sleep quality improvements