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Coverage is targeted rather than universal, focusing on those with the greatest potential health benefit

Do you need to stay on GLP-1s forever

Experience in patients with type 2 diabetes shows that the dosage must be continually increased unless lifestyle changes are made

This keeps metabolism active and prevents the caloric creep that causes plateaus

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On the other hand, Akkermansia muciniphila can activate immune cells in the intestine, such as macrophages and dendritic cells, to secrete the anti-inflammatory cytokine IL-10 and inhibit the inflammatory response (Mei et al., 2024)