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SOD2 is localized in the mitochondria, and its impairment post-stress may indicate high oxidative damage and mitochondrial dysfunction

It has a range of pharmacological activities, like anti-tumor activities, chemo-prevention, and cardio-protection

Compared with wild-type parasites, EXP1 knockout parasites showed a reduced frequency of channel detection by patch clamping, and transgenic parasites expressing limiting levels of EXP1 were hypersensitive to low levels of amino acids

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Int J Mol Sci 2022;23(15):8318

Oxidative stress drives CD8+ T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes