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[3] [5] These symptoms typically peak within the first few days after each dose increase and gradually diminish as the body adapts to the medication

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87 Although this rate was slightly lower than that observed in non-surgical controls (1.93 per 1 000 person-years), Cox regression analysis indicated no statistically significant difference in fracture risk (HR = 0.96, 95% CI: 0.831.11), suggesting that VSG may not substantially increase fracture incidence