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There are various mechanisms through which berberine interacts with GLP-1 to regulate blood glucose levels

This powerful peptide plays a key role in promoting feelings of trust, connection, and well-being

The interplay of local (within the diseased liver) and systemic inflammation, stemming from portal hypertension and alterations in the gut microbiome, alongside heightened levels of circulating cytokines, disrupts hepatic vagal neurogenic responses and impacts cerebral endothelial cells, giving rise to neuroinflammation

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This study reported an incremental cost-effectiveness ratio (ICER, the additional cost required to gain one QALY) of 3,684 per QALY, well below the UK willingness-to-pay (WTP) threshold of 20,000 per QALY, indicating high cost-effectiveness