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The failure was about lobbying weight and the legislative priority queue

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While mTORC2 primarily promotes cell proliferation and survival through the phosphorylation of AKT, many tumors need mTORC1 to maintain their ability to control protein synthesis and cell growth, as well as to coordinate nutrient and energy supply to ensure that they undergo unrestricted cell division (103)

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Getting these conversions wrong is one of the most common mistakes researchers make, and it leads to either underdosing (wasted time) or overdosing (excessive side effects)

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