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Plain Language Summary: People living with type 2 diabetes have a higher risk of serious vision problems, including legal blindness and a condition called ischemic optic neuropathy, which occurs when the optic nerve does not get enough blood flow

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Nayan (12:37) Gosh, that's a really, really good question, Taylor

For example, pGlu modified beta-amyloid peptides (pGlu-A) aggregate much faster compared to non-pyroglutamic ones and form toxic oligomers that may damage neurons

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This could be because the underlying cause of high oxidative stress in diabetes is not removed, and more exogenous GSH is simply converted to GSSG without a change in the redox ratio