Nov 2015;104(5):1074-81
The therapeutic era of peptides began in 1921 with the discovery of insulin, a breakthrough that revolutionized diabetes and helped establish biologic therapies in medicine Since then, peptide hormones like oxytocin and human growth hormone (GH) have entered clinical use, and glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide are now widely prescribed for obesity and metabolic diseaseconditions increasingly recognized for their effect on orthopaedic outcomes
Andrew Huberman: Okay, so we've talked about these plant-based compounds, the omega-3s and D3, unless there's something else that you just absolutely must throw into the mix, I probably will return us to the conversation that I opened up with, which is about cold and heat, which admittedly I pulled us off that path, so I take full responsibility for that
A new Cleveland Clinic analysis of nearly 8,000 patients suggests that discontinuing semaglutide and tirzepatide, on average, does not lead to significant weight regain in clinical practice, as many patients later restart the original medication or try an alternative obesity treatment
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Xu Z, Liu Y, Ma R, Chen J, Qiu J, Du S, et al
