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Additionally, ketamine activates the NLRP3 inflammasome, inducing caspase-1 activation and neuronal pyroptosis, further contributing to neuroinflammation in regions, such as the hippocampus and prefrontal cortex (Zhang et al., 2021)

Some report noticing changes within days, while others use BPC-157 consistently for several weeks before noticing a difference

This two-part approach helps doctors see if the treatment is working