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For example, Lee et al (97) demonstrated that hydrogen peroxide can oxidize cysteine residues in PTEN, forming a disulfide bond between Cys124 and Cys71, leading to PTEN inactivation
The formation of self-propagating aggregates by the yeast prion proteins generally leads to a loss-of-function of the native protein and subsequently the appearance of a novel phenotype, which can be transmitted to daughter cells and meiotic progeny by cytoplasmic inheritance (Liebman and Chernoff, 2012
The dual role of oxidative stress in atherosclerosis and coronary artery disease: pathological mechanisms and diagnostic potential
While a high concentration of free radicals could damage the living process, a low concentrations could prevent infections
These pathological manifestations have been found in the early stages of AD development as well as preclinical AD
