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Additionally, the liver is the primary site for synthesizing GSH, considered the major intracellular antioxidant [90,93]

In diabetic state, hyperglycemia leads to overproduction of free radicals (i.e., mitochondrial , NO and peroxynitrite) mainly derived from glucose oxidation and lipid peroxidation, which cause oxidative damage to biomolecules

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However, in late 2017, a once-weekly GLP-1 diabetes drug hit the market, and people with diabetes now had the option of a weekly injection instead of a daily injection

any visual change signals potential degradation