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A 2022 meta-analysis found NMN increased blood NAD+ by 42% and NR by 28% at 500mg daily dosesboth significantly outperform direct NAD+ supplementation in bioavailability

Figure 3 Oligomeric A 40 Induces Inflammation Which Is Modulated by GGC Treating human brain cells with oligomeric A 40 significantly decreased the level of the anti-inflammatory cytokine IL-10 (Figure 4A) and increased the levels of the pro-inflammatory cytokines, TNF-, IL-6 and IL-1 compared to non-treated cells (Figures 4BD)

Additionally, stopping GLP-1 therapy abruptly triggers a rebound in hunger hormones and can leave patients feeling more famished than before treatment began

Benefits in High-Risk Patient Groups GLP-1 receptor agonists also show heart-protective effects in other vulnerable groups

See your general practitioner (GP) if you are concerned