Apart from redox reactions, NAD + is also a donor of ADP-ribose through enzymes such as poly (ADP-ribose) polymerases (PARPs) involved in DNA repair 6
In this regard, kojic acid-loaded SLNs showed higher drug concentration within the skin layers, controlled drug release, and greater tyrosinase inhibition capability was seen in comparison to the conventional formulation (Khezri et al., 2020b)
Citrate and glutamine were elevated suggesting an impact on anaplerotic metabolism of TCA intermediates to amino acid backbones and other pathways 37
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