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NAD+ and glutathione naturally decline with age , contributing to cellular dysfunction, oxidative stress, and increased risk of chronic diseases like Alzheimer's, Parkinson's, and metabolic disorders

The efficacy, safety and tolerability of ALC were studied during a double-blind, placebo-controlled, 12-week trial in patients with initial dementia caused by AD and vascular dementia (VD)

Treatment decision-making should focus on individualised holistic treatment, requiring clinical judgement to balance the efficacy and safety of treatments with confounding health factors

Staying active can slow or prevent most age-related health problems

Combination therapies may be useful to prevent praziquantel resistance even if only partial worm reductions were affected by the new drug alone

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