This slow titration reduces gastrointestinal side effects, which remain the most common adverse eventsnausea, vomiting, constipation, and diarrhea occur in a significant subset of users
Patients interested in using ispaghula as part of a broader metabolic health strategy should discuss this with their GP or diabetes specialist nurse, particularly if they are already taking glucose-lowering medications, as adjustments may be needed to avoid hypoglycaemia
The timeline question of when side effects begin varies by individual but most people notice GI effects within the first few days of each dose increase
Change in butyrate producers (such as Roseburia , Eubacterium and Butyrivibiro ) in feces and in the small intestine was observed in both studies, but increase in butyrate levels were observed only in one (108)
Higher levels of HDL are associated with a reduced risk of heart disease and stroke
Tooth decay and gum disease lead to the release of volatile sulfur compounds (VSCs), a type of bacterial waste