glutathione overview of its protective roles measurement and biosynthesis The “Glutathione Pathway.” synthesis, γ-glutamyl pathway, Frontiers | Glutathione: A Samsonian

L.HoR.WangX.et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Taskilar K., Hagen M., Kleyer A., Simon D., Reiser M., Hueber A.J., Manger B., Englbrecht M., Finzel S., Tony H.-P., et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Srinivasan, D., Nathan, S., Suresh, T

Cell 21, 92101

CB-839 is a highly potent allosteric inhibitor that completed phase I clinical trials in March 2019 in patients with advanced RCC (NCT02071862) and has in 2020 moved to phase II clinical trials in patients with non-small cell lung cancer (NCT04265534)

Bialecka M, Kurzawski M, Klodowska-Duda G, Opala G, Juzwiak S, Kurzawski G, et al