Moreover, it has been found that mitochondrial functions and integrity can be affected by many of the risk factors of ASD, including toxins, immune activation, medicines, and metabolic disturbances [17]
Experiments with fasted and calorie-restricted rats showed increased mRNA concentrations of acyl-CoA and CPT-1 in the liver, heart and kidneys compared to control animals due to upregulation of PPAR [111]
doi: 10.3389/fnut.2023.1134162 Received 30 December 2022 Accepted 22 June 2023 Published 20 July 2023 Volume 10 - 2023 Edited by Xiaoping Yang, Hunan Normal University, China Reviewed by Lorenzo Lorusso, ASST Lecco, Italy
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