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This mechanism enhances endothelial proliferation, promotes new capillary formation, and increases blood flow to damaged tissues, which is critical for delivering oxygen and nutrients to healing areas

and 6:00 p.m [10, 19]

FIGURE 1 2.2 OS markers in MS Although the precise etiology of MS remains incompletely understood, OS is widely recognized as a pivotal contributor to disease pathogenesis ( in vivo OS status ( In parallel, alterations in endogenous antioxidant defense systems have been consistently observed in MS

To prevent receptor downregulation, a weekly schedule of 5 days on followed by 2 days off is widely documented in literature